Lofa in, Mebane out

Middle linebacker Lofa Tatupu will play – and start against the 49ers. But defensive tackle Brandon Mebane is among the Seahawks inactive players. Craig Terrill will start for Mebane at the three-technique spot.

Also inactive:
CB Travis Fisher
LB Leroy Hill
C Chris Spencer
OT Walter Jones
WR Deion Branch
DT Michael Bennett
3rd QB: Mike Teel

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